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In its 85-year story, the mission of our institute has been to carry out excellence research in fundamental and applied physical chemistry, contributing to the scientific training of several generations of researchers at the highest level. Our vision is to be an international reference in multidisciplinary research focused on the resolution of the present challenges of our society in the fields of health, biotechnology, new materials, and environment.

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June 2018
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Enzybiotics are a novel class of antibacterials, based on the peptidoglycan lysins, which kill rapidly and specifically the bacteria, preventing the appearance of crossed resistances with other pathogens and the microbiota degradation.

Pathogens try to escape from our immune system by mutating their proteins. To prevent the bacterium from infecting the cells with a single mutation, the NAIP5 protein of the inflammosome is capable of detecting bacterial flagellin at several sites.

The notion that strong laser light can intervene and modify the dynamical processes of matter has been demonstrated and exploited both in gas and condensed phases.

The i-motif is four-stranded DNA structure stabilized by hemiprotonated cytosine base pairs (C:C+). Although this is a very attractive structural motif for the development of devices at a nanometric scale, the requirement of acidic pH for its formation makes the i-motif occurrence in vivo controversial.

Statistics from structural genomics initiatives reveal that around 50-55% of the expressed, non-membrane proteins cannot be purified and therefore structurally characterized due to solubility problems

Processes catalyzed by enzymes offer numerous advantages over chemical methods although in many occasions the stability of the biocatalysts becomes a serious concern. 

In collaboration with BRUKER Española S.A., the SEBBM has awarded Dr. Antonio Chaves-Sanjuán with the “José Tormo” Prize 

Dr. M.J. Sánchez-Barrena, contracted researcher at Institute “Rocasolano”, has been awarded with a very competitive “Leonardo” fellowship from the BBVA Foundation.

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