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In its 88-year story, the mission of our institute has been to carry out excellence research in fundamental and applied physical chemistry, contributing to the scientific training of several generations of researchers at the highest level. Our vision is to be an international reference in multidisciplinary research focused on the resolution of the present challenges of our society in the fields of health, biotechnology, new materials, and environment.

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This presentation will describe the use and development of structure determination methods, specifically cryo-electron microscopy (cryo-EM) and microcrystal electron diffraction (MicroED).

The frontispiece of the journal Chemistry Eur J highlights the adaptability of gemcitabine.

In the current year 2021, the Institute of Physical Chemistry Rocasolano (IQFR) reaches 75 years of activity in the Rockefeller building.

Researcher from the IQFR-CSIC publishes a comprehensive review article on recent advances of the time-resolved serial crystallography technique at synchrotron radiation sources in Crystals journal.

Scientists from the IQFR and Univ. Complutense of Madrid have synthesized and characterized the first phasing agent designed for solving protein structures at the maximum intensity of the synchrotron facilities.

"La importancia de conocer las proteínas para detener al virus" es el título de las actividades divulgativas que miembros del grupo de RMN de proteínas han emprendido en centros educativos IES de Madrid.

Scientists from the IQFR and the University of Oxford reveal how a family of proteins, essential for inositide and phosphate metabolism in eukaryotes, act on three types of key compounds.

The journal Chemistry Eur J highlights in its cover the first structure of a new type of DNA/ligand complex where selective recognition of interfaces between different DNA secondary structures is observed for the first time.