Research

Research

The “chameleonic” peptide LytA239-252 forms a β-hairpin in aqueous solution which is converted into an α-helix in the presence of micelles. We have found that the balance of hydrophobicity <H> and amphipathicity <μH> contributes to helix stability.

Geochemical analyses in a Greenland ice core reveal a significant increase in atmospheric iodine concentrations as a consequence of the raise in human-induced tropospheric ozone and Arctic sea-ice retreat. A multidisciplinar research led by CSIC researchers reconstruct the iodine atmospheric fluxes since the onset of the Industrial Revolution.

The lytic transglycosilase Slt is critical in the cell wall recycling in Pseudomonas aeruginosa, as well in antibiotic resistance. Our structural work results disclose the details of bacterial response mediated by Slt to the b-lactam antibiotic challenge.

We have grown high quality magnetite microcrystals conserving bulk magnetic properties below 20 nm thickness. The observed domain configurations are dictated purely by shape anisotropy thus demonstrating the possibility of designing spin structures in ultrathin, magnetically soft magnetite at will.

PBP2x is an essential transpeptidase in Streptococcus pneumoniae, critical for septal peptidoglycan synthesis during cell division. Recognition of nascent peptidoglycan at an allosteric site located in the PASTA domains of this enzyme predisposes penetration of peptidoglycan into the active site for turnover events.